10 exam-style questions with answers and explanations, straight from our 1,030-question bank. Tap an answer to check yourself. When you're ready, take the scored version in the free practice test.
The PA-CP exam has 120 questions and runs 2 hours.
These 10 free PA-CP questions are organized by exam domain, so you can see how each part of the Certified Physician Assistant - Pediatrics blueprint is tested. Reveal the answer and explanation under each question.
Domain 1: Health Maintenance
Question 1
A previously healthy, term 46-day-old infant is evaluated for a rectal temperature of 38.3°C. The infant is alert, feeds well, and has no focal findings. Catheterized urine contains leukocyte esterase and 25 leukocytes per high-power field. Procalcitonin is 0.08 ng/mL, C-reactive protein is 3 mg/L, and the absolute neutrophil count is 2,300/µL. Blood and urine cultures have been collected. The parents prefer home care, have reliable transportation and telephone access, and can return for reassessment tomorrow. Under the AAP pathway for well-appearing febrile infants aged 29-60 days, which plan accommodates that preference?
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Correct answer: A - Begin oral antibiotics without routine lumbar puncture; reassess within 24 hours
Domain 2: Infectious Diseases
Question 2
At a preventive visit, the immunization record of an immunocompetent 16-year-old shows two HPV vaccine doses: one at age 12 years and the other three months later. No additional HPV doses were given. Using the AAP 2026 immunization schedule, what is needed to complete the series?
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Correct answer: D - One additional dose now, because the first two were too closely spaced
Domain 3: Cardiovascular Disorders
Question 3
An 18-month-old has been pulling at both ears since yesterday. Temperature is 38.2°C, and the child is drinking normally. Both tympanic membranes are moderately bulging with middle-ear effusions. Thick yellow discharge coats both conjunctivae. There are no medication allergies or antibiotics in the past month. In addition to analgesia, which treatment is preferred?
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Correct answer: C - Oral amoxicillin-clavulanate as the initial antibiotic
Domain 4: Psychiatry and Behavioral Medicine
Question 4
Evaluation of a 9-year-old with slowing linear growth and iron-deficiency anemia includes a negative tissue transglutaminase IgA result. Total serum IgA is below the assay’s detection limit. The child continues to eat bread and other gluten-containing foods daily. Celiac disease remains a concern. Which test would best address the limitation of the initial antibody result?
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Correct answer: B - IgG tissue transglutaminase antibody testing
Domain 7: Musculoskeletal Disorders
Question 5
Before an adolescent follow-up visit, a 16-year-old completes the PHQ-9 modified for teens. The total score is 8. On the item asking about thoughts of being better off dead or self-harm, the response is “several days.” The PA has not yet discussed that response with the patient. What does this combination of results require during today’s visit?
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Correct answer: D - Assess suicidal thoughts, intent, plan, and access to lethal means directly
Domain 8: Sports Medicine
Question 6
At an asthma review, a 9-year-old reports cough or wheeze about once a week, no activity limitation, and one nighttime awakening in the past month. FEV1 is 96% of predicted. However, three exacerbations during the past year required oral corticosteroids. The child uses albuterol correctly but has never received a controller. Applying the NAEPP framework for both impairment and future risk, which initial regimen is most appropriate?
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Correct answer: A - Daily low-dose inhaled corticosteroid, with albuterol as needed
Domain 11: Hematology/Oncology
Question 7
A 5-year-old develops petechiae and several small bruises two weeks after a respiratory illness. Platelet count is 12,000/µL; hemoglobin, leukocyte count, and the remainder of the peripheral smear are normal. There is no mucosal bleeding, hematuria, organomegaly, bone pain, or systemic illness. Pediatric hematology agrees that the presentation is typical of newly diagnosed immune thrombocytopenia and can review the child in 48 hours. The family can reliably follow bleeding precautions. How should this child be managed today?
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Correct answer: D - Observe as an outpatient with bleeding precautions and hematology follow-up
Domain 12: Endocrine Disorders
Question 8
A 13-year-old with a BMI at the 97th percentile returns because right knee pain has persisted for three weeks. There was no injury. Knee radiographs and the knee examination are normal, but the child walks with the right foot turned outward. Internal rotation of the right hip is restricted, and flexing that hip causes obligatory external rotation. Which diagnosis best localizes the source of the knee pain?
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Correct answer: C - Slipped capital femoral epiphysis
More PA-CP practice questions
Question 9
Within minutes of eating a cookie containing peanuts, an 8-year-old with a known peanut allergy develops wheezing, a hoarse voice, and dizziness. Weight is 26 kg, blood pressure is 72/38 mmHg, and oxygen saturation is 91%. There are no hives. The child remains conscious with a palpable pulse; emergency support is being initiated. Epinephrine 1 mg/mL is available for preparation of a weight-based dose. Which medication order should be carried out first?
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Correct answer: B - Epinephrine 0.26 mL of 1 mg/mL intramuscularly in the anterolateral thigh
Question 10
Routine critical congenital heart disease screening is performed on a well-appearing term newborn at 28 hours of age. On room air, oxygen saturation is 96% in the right hand and 94% in a foot. One hour later, repeat measurements with reliable waveforms are again 96% and 94%. The infant has no murmur or visible cyanosis. Under the AAP’s revised 2025 screening algorithm, how should the second result be handled?
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Correct answer: B - Record a failed screen and evaluate the hypoxemia before discharge